Gait Asymmetry in People With Parkinson’s Disease Is Linked to Reduced Integrity of Callosal Sensorimotor Regions

نویسندگان

  • Brett W. Fling
  • Carolin Curtze
  • Fay B. Horak
چکیده

Background: Individuals with Parkinson’s disease (PD) often manifest significant temporal and spatial asymmetries of the lower extremities during gait, which significantly contribute to mobility impairments. While the neural mechanisms underlying mobility asymmetries within this population remain poorly understood, recent evidence points to altered microstructural integrity of white matter fiber tracts within the corpus callosum as potentially playing a substantial role.

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تاریخ انتشار 2018